Bioreactor
RICH SMART TECH headquarter is in Xi'an City which located in the heart of China; includes several production bases, own professional research and development team 20+ persons; Our modern factory covers an area of 9,600 m2. Our company is equipped with highly automated processing equipment to save manpower, reduce manual deviations and improve the company's competitiveness.Our product lines range from laboratory size ,pilot scale to industrial production as, bioreactor & fermenter vessels,Customized stirrer tanks ,Grinder, Granulator, tablet press machine, capsule fill machine, mixer, drying machine,liquid filling machine,powder filling machine,Mixing Homogenize reactor,Solvent recovery system,Filtration system,IBC bin tank, laboratory instrument ,etc.
Why choose us
Our Certificates
RICH SMART Company has passed ISO 9001, and our products have passed CE, TUV, BV, SGS, PED, and ATEX standard certifications.
Production Equipment
Our factory is equipped with lathes, milling machines, drilling machines, sawing machines, bending machines, shearing machines, and more.
Quality Control
We implement strict quality control at every stage, from raw material procurement and processing to production details and final product testing. Each process undergoes rigorous QC/QA inspection.
Our Services
Our excellent engineering team provides flexible and customized services through effective communication and research, turning your project requirements into real business opportunities and profits.
Bioreactor
A bioreactor provides an ideal environment where cells can focus on what they are supposed to do: proliferate. Like lab workers, cells can only produce consistently good work if the conditions are right: It should not be too hot or too cold, and they have to have enough nutritious food and fresh air. In terms of a bioreactor, this means maintaining pH, temperature, ensuring sufficient gas supply and, depending on how the instrument has been configured, adding nutrients for successful maintenance of growth.
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Type of bioreactor |
Applications |
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Stirred tank fermenter |
Antibiotics, citric acid, Exopolysaccharides, cellulose, Chitinolytic enzymes, Laccase, Xylanase, Pectic, and pectate lyase, Tissue mass culture, Lipase, Polygalacturonases, Succinic acid |
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Bubble column fermentor |
Algal culture, Chitinolytic enzymes |
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Airlift fermentor |
Antibiotics, Chitinolytic enzymes, Exopolysaccharides, Gibberelic acid, Laccase, Cellulase, Lactic acid, Polygalacturonases, Tissue mass culture |
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Fluid bed fermentor |
Laccase |
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Packed bed fermentor |
Laccase, Hydrogen, Organic acids, Mammalian cells, |
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Photobioreactor |
Wastewater treatment, water quality management, remediation of contaminated soil |
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Membrane bioreactor |
Alginate, Antibiotic, Cellulose hydrolysis, Hydrogen production, Water treatment, VOCs treatment |
Bioreactor Materials
The choice of materials for constructing a bioreactor is essential for ensuring the durability, reliability, and sterility of the system. Some common materials used for bioreactor construction include:
Stainless steel
Widely used for large-scale bioreactors due to its durability, corrosion resistance, and compatibility with steam sterilization.
Glass
Commonly used for smaller-scale bioreactors due to its transparency, chemical resistance, and compatibility with steam sterilization.
Polymers and plastics
Used for disposable, single-use bioreactors and components, offering advantages in terms of cost, sterility, and disposal.
Custom Bioreactor Systems
Material: 316L stainless steel with material contact to the other 304 stainless steel
Control system: Siemens PLC, industrial LCD touch computer control, parameters can be set to store, can be remotely connected to the computer through the USB interface, the data
The main material of the fermenter is made by 316Lstainless steel.
The design pressure: P(inside)= 0.3Mpa, P(interlayer)= 0.3Mpa, The polishing precision: Ra0.4～0.6, the ratio between diameter and height: 1:2.3
Sterilization method ：Auto sterilizing in situ
Stirring system
Mechanical sealing system at the top of the fermenter; high-powered stirring oar, antifoam oar; AC electrical machine: Infinite speed variation; rpm in the fermenter: 70~1２00rpm±1%,The height of the stirring oar can be adjusted, too.
Temperature detection and control
Heat by thermostatic water tank and circulate by circulating pump(Grundfos, Denmark), autocontrol (cooling water+5℃)~65℃±0.1℃，temperature probe(US)
PH Detection And Control
2.00-12.00±0.05pH, Autocontrol By Adding Acid And Base, PH Sensor (Mettler, Switzerland) And Shielding Lead (Mettler, Switzerland). Fermenter Is Autocontrolled With Peristaltic Pump
DO Detection And Control
0-150±3% Displaying Precision 0.1%, Sensor (Mettler, Switzerland) And Shielding Lead(Mettler, Switzerland)
Feed Control
Fermenter Uses Peristaltic Pump (Longer) To Add Meterials
Antifoam Control
Tested By Sencor And Added Antifoamer By Peristaltic Pump
Design options
Available in coated black steel and coated or uncoated stainless steel
Customized Electrical accessories of internationally renowned brands such as Siemens, Mettler, Hamilton, etc.
Complies with GMP standards and meets most customer needs
CE and ATEX systems available
Custom designed systems e.g. where space limitations disqualify the use of standard systems
Tailor-made split units e.g. for retrofit projects
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Parameter |
Description |
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Total volume |
5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL etc. |
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Working volume |
30%~70% |
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Tank |
Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of |
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Stirring system |
Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle |
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Sterilization |
Sterilize in place(SIP), auto control by program |
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Clean |
Clean in place (CIP) by spray ball |
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Gas control |
Control by rotor meter, air flow 1 vvm |
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Feeding |
Automatically feeding by peristaltic pump |
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Anti-foam control |
Automatically add antifoam by peristaltic pump |
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Temperature control |
Auto-control, electric heating range: water source add 5℃ to 70℃ |
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PH control |
PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland. |
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Do control |
0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen. |
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Sampling |
Sampling valve, can sterilization separately, manual |
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Harvest |
Zero dead zone bottom valve(Gemu/Burket,Germany), can sterilization separately, manual/auto |
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Lid lift system |
30L-500L have lid lift system, 700-1000L have human hole. |
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Pressure |
Auto control, BD Germany pressure transmitter |
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Exhaust |
Have condenser before exhaust, control by diagram valve / Proportional control valve. |
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Control parameters |
10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data |
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Optional configuration |
Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas flow 2vvm, gas(CO2) exhaust analysis, Level sensor, |
Packaging & Shipping
Packaging:
-After use cartons inside, outside with wooden case packaging;
-Both neutral and customized packaging can be available.
Shipping:
-We can ship the goods to you by International Express such as DHL, TNT, EMS, FedEx and so on and you can also choose the appropriate one based on your timeline and budget. Besides, you can definitely choose to use your own shipping agent.
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Shipping method |
Note |
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Express |
Door to door, very convenient, don't need to clearance or pick-up |
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By air |
Airport to an airport, you need to do the customs clearance and pick up the goods at your local airport, which you can have a local shipping agent to do for you. |
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By sea |
Port to port and you need to do the customs clearance and pick-up the goods at your local port, which you can have a local shipping agent to do for you. |
Certificate
FAQ
We're professional bioreactor manufacturers and suppliers in China, providing customized industry production solutions to nearly 4,500 companies. We warmly welcome you to wholesale bulk bioreactor for sale here from our factory. For price consultation, contact us.
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