Glass Bioreactor Vessel

 

The RICH SMART Microbial Fermentation Glass Bioreactor Vessel system is a reaction system with flexible combination, comprehensive functions and easy operation. It can be used for batch, fed-batch, continuous/perfusion culture processes, and integrates online glucose/lactic acid detection and tail gas analysis. It adopts magnetic mechanical stirring with servo motor. The stirrer can be sterilized as a whole with the glass tank to avoid contamination. It can be used for a variety of cell/microorganism culture, and the software is localized, with a high user-friendly interface. It is widely used in research and development centers such as synthetic biology/monoclonal antibody/vaccine companies, laboratories of universities/science centers, etc.

1. The inside and outside of the tank are mirror polished, and different types of stirring paddles can be customized;
2. Professionally designed stainless steel bottom annular gas distributor, equipped with fermentation-specific baffles, high mass transfer efficiency;
3. Designed with mechanical pressure defoaming blades and defoaming electrodes, the defoaming effect is good.
4. Servo motor, small size, fast response, no delay in starting;
5. Various parameters can be set, such as temperature, pH, dissolved oxygen, speed, defoaming, feeding, etc.;
6. The process program can be edited according to the needs of the fermentation formula to automatically control the temperature, pH, DO, speed, defoaming and feeding;
7. A variety of related feeding strategies can be provided, such as PH, DO index feeding mode, linear feeding mode and segmented feeding mode;
8. It can be connected to a host computer for detection parameter analysis and comparison; It can save at least 1,000 batches of fermentation data and can check the history.

The pipelines in contact with the material are all 316L sanitary stainless steel pipes and fermentation-specific valves

Argon gas protection welding, in line with the requirements of microbial fermentation, no dead corners, no residue

Optional accessories

1. Fully automatic electric heating steam generator.
2. Industrial chiller.
3. Oil-free air compressor, air dryer, gas storage tank.

4. Oxidation-reduction potential, tail gas O2, CO2 content, methanol (ethanol) content, sugar concentration, cell concentration, etc.
5. Multi-channel feeding, feeding weighing, tank weighing, fully automatic sterilization, etc.
6. Microbubble device, multi-gas mixing device, oxygen inlet bypass, etc.

1.Cell Culture & Biotechnology,
Mammalian cell culture ,Insect cell culture ,Microbial fermentation (bacteria, yeast, fungi),Algae and cyanobacteria cultivation

2.Pharmaceutical & Vaccine Production,
Monoclonal antibody (mAb) development,Recombinant protein production,Viral vaccine production

3.Stem Cell & Regenerative Medicine
Expansion of mesenchymal stem cells ;Induced pluripotent stem cell culture;3D cell culture

4.Research & Process Development
Bioprocess optimization and scale-up studies;Metabolic engineering and synthetic biology;Anaerobic/microaerophilic microbial studies

5.Industrial & Environmental Biotechnology
Enzyme production (e.g., amylases, lipases);Biofuel research (e.g., ethanol, biodiesel);Wastewater treatment studies (microbial consortia)
6.Education & Training
Academic teaching labs (fermentation, cell culture techniques);Pilot-scale training for bioprocessing

How often should we clean or sterilize the glass bioreactor?

The cleaning and sterilization process for glass bioreactors follows each usage to avoid exposure to different substances between experiments. A complete cleaning followed by sterilization must occur before every usage, and the timeframe between cleanings depends on protocol requirements.

Can I autoclave my entire glass bioreactor setup?

Autoclave treatment tolerates most borosilicate glass vessels along with specific components. The autoclaving process requires you to take out any electronics or sensors that may suffer damage and all components that are not autoclavable. Readers should check manufacturer manuals to verify if their products are suitable for autoclaving.

What cleaning agents are safe for glass bioreactors?

Laboratory-grade detergents that support glass cleaning should be used with a non-abrasive nature. Select cleaners only when recommended professionals state alkaline and acidic substances are acceptable. Clear the glass surface using deionized water to avoid the buildup of residue.

What's the difference between SIP and autoclaving?

The components of autoclaving go into steam chambers for sterilization, but Steam-In-Place (SIP) uses piped steam to sterilize entire bioreactor systems in their assembled state. SIP suits the sterilization needs of big integrated units that resist easy relocation.

How can I prevent thermal shock when cleaning or sterilizing?

Avoid sudden temperature changes. Cold liquids or rinses should only be applied when hot glass has cooled to room temperature. This method prevents thermal stress-induced cracks and breakage.

Our high-quality Glass bioreactor have been successfully implemented in numerous global projects, earning high praise from clients. Each Glass bioreactor is securely packed in export-grade wooden crates with reinforced cushioning to ensure damage-free worldwide delivery.

Xi'an Rich Smart Technology Co.,,Ltd has own specialized factory, we implement precision thermal manufacturing processes that fully comply with international industry standards. Our automated production line delivers structurally sound, long-lasting equipment through energy-efficient operations. This standardized yet optimized manufacturing approach not only ensures product reliability but also significantly boosts cost-effectiveness, giving our bioreactors superior market competitiveness while maintaining consistent quality across all batches.

We ensure full compliance with international market requirements. Our bioreactors and equipment hold the following export certifications:CE,cGMP,ISO,ATEX ,RoHS,etc
Our certifications ensure seamless market access and demonstrate our commitment to quality, safety, and international compliance.

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