Stainless Steel Bioreactor
Your Professional Stainless Steel Bioreactor Supplier
RICH SMART TECH is headquartered in Xi'an City, located in the heart of China. It includes several production bases and has its own professional research and development team of over 20 members. Our modern factory covers an area of 9,600 m² and is equipped with highly automated processing equipment to save labor, reduce manual deviations, and improve the company’s competitiveness.
Our product lines range from laboratory-scale to pilot-scale and industrial-scale production. These include bioreactors and fermenter vessels, customized stirrer tanks, grinders, granulators, tablet press machines, capsule filling machines, mixers, drying machines, liquid filling machines, powder filling machines, mixing homogenizing reactors, solvent recovery systems, filtration systems, IBC bin tanks, laboratory instruments, and more.
why choose us
Our Certificates
RICH SMART TECH has passed ISO 9001 certification. Our products have also obtained CE, TUV, BV, SGS, PED, and ATEX certifications.
Production Equipment
Our factory is equipped with lathes, milling machines, drilling machines, sawing machines, bending machines, shearing machines, and more.
Quality Control
We implement strict quality control at every stage—from raw material procurement and processing to production and final product testing. Each step undergoes rigorous QC/QA inspection.
Our Services
Our excellent engineering team provides flexible and customized services through effective communication and research, turning your project requirements into real business opportunities and profits.
Stainless Steel Bioreactor
Stainless steel bioreactors are special containers made of stainless steel. They are used for processes like fermentation, growing cells, and chemical reactions. These bioreactors provide a controlled space needed for bioprocessing.
Standard Type Specifications
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Stainless Steel Bioreactor |
Range indicators |
Accuracy |
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Power supply |
220V/50HZ |
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Diameter-to-height ratio |
About 1:2 |
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Volume |
5L,10L 15L 20L ,50L,100L,200L,500L,1000L ,2000L,3000L.......50000L (lab scale to industry scale is available) |
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Material |
SS316L contact Vessel and SS304 jacket |
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Sterilization |
Online steam sterilization |
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Stirring |
Top mechanical stirring (Magnetic drive stirrer is option) |
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Stirring speed |
50~1000rpm (50L and below) |
±1rpm |
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PH |
0.00-14.00 |
±0.01 |
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pH³ |
2.00-12.00, peristaltic pump flow plus acid and alkali control |
±0.02 |
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DO |
0~150%, can be linked with speed, pressure, ventilation, and feeding control |
±3% |
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Temperature |
0-150℃ |
±0.1℃ |
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Cooling water temperature |
5-65℃ |
±0.2℃ |
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Foam |
Defoaming electrode automatically detects foam level, and peristaltic pump automatically adds defoaming agent |
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Control method |
PID intelligent fuzzy control, high control accuracy, not easy to fluctuate |
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Ventilation |
Top and bottom ring ventilation, optional four-way gas (Air/O²/N²/CO² mass flow meter) |
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Exhaust gas |
With tail gas condenser (500L and below) |
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Pump/feeding |
Fixed and variable speed peristaltic pumps are used for adding acid, alkali, defoamer and materials, etc. |
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Customizable |
Liquid level control, feed weighing system, two-way feed, online detection of methanol and ethanol content, exhaust oxygen and carbon dioxide detection, etc. |
High-quality stainless steel material:
Made of high-quality stainless steel, with good corrosion resistance and high temperature resistance, in line with health standards.
The internal surface is smooth and easy to clean, reducing the risk of cross-contamination.
Easy to use:
Compact design, friendly operation interface, easy for users to set up and monitor.
Equipped with basic temperature control, pH monitoring and stirring functions, suitable for small experiments and production.
Adjustable parameters:
Support the adjustment of key fermentation parameters such as temperature, pH and stirring speed to meet the growth needs of different microorganisms. It can be flexibly adjusted according to the specific process requirements.
Energy saving and high efficiency:
Improve fermentation efficiency and reduce energy consumption through optimized design and efficient mixing system.
Key Features You Can Trust
Our stainless steel bioreactors boast a range of features that serve to enhance user experience and boost productivity:
Robust Construction:
Built to withstand extreme operational conditions.
Scalability:
Models available for small-scale testing or large-scale production.
Automation Options:
Seamless integration with existing systems for automated operations.
User-friendly Design:
Intuitive controls and easy access for maintenance and cleaning.
Its Main Components And Functions Include:
Reaction Vessel: Made of high-quality stainless steel, the vessel is typically jacketed for temperature control. It houses the culture medium and provides a sterile environment for cell growth.
Agitation System: Consisting of a stirrer and impeller(s), this component helps to mix the contents of the vessel evenly, ensuring that nutrients are distributed throughout and oxygen is supplied to the cells. The agitation speed can be adjusted to minimize shear stress on sensitive cells.
Temperature Control: Often featuring a double-walled design with a circulating water or oil jacket, the vessel can be connected to a thermostat-controlled heating/cooling system to maintain the optimal growth temperature for the organisms.
Aeration System: A sparger or gas diffuser introduces air or pure oxygen into the culture to provide the necessary dissolved oxygen for aerobic cultures. The gas flow rate can be regulated to control DO levels.
PH Control System: Equipped with pH probes and acid/base dosing pumps, the bioreactor allows for real-time monitoring and automatic adjustment of the culture's pH to maintain the ideal condition for cellular metabolism.
Level Sensor: To manage the liquid level inside the bioreactor, it might have a sight glass or an electronic level sensor.
Sampling Ports: Sterile sampling ports enable researchers to take samples for analysis without compromising the sterility of the system.
Automation and Control: The bioreactor comes with a control panel that integrates data acquisition software, allowing users to program and monitor various process parameters such as temperature, pH, agitation speed, and DO levels.
Sterilization Capabilities: The bioreactor is designed for easy cleaning and sterilization either manually or via a built-in CIP (Cleaning-in-Place) or SIP (Sterilization-in-Place) system.
Accessories: Additional accessories may include probes for measuring biomass, dissolved gases, or metabolites; clamps and seals for securing ports and tubes; and connectors for attaching tubing for nutrient feed, waste removal, and sampling.
Installation phase
On site preparation: Ensure that the installation area is clean, level, dust-free, and complies with biosafety and electrical safety regulations Arrange appropriate support foundations or frames according to the weight and size of the equipment.
Equipment positioning: Use appropriate lifting tools and personnel, and correctly handle and place the main body and ancillary equipment of the bioreactor according to the instructions, such as controllers, power equipment, pipelines, and instruments.
Pipeline connection:
Install inlet and outlet pipelines, circulation pipelines, ventilation pipes, cleaning liquid pipes, sewage pipes, etc., and ensure that all connections are sealed reliably to avoid leakage.
Electrical installation:
Professional electricians shall complete the installation of power cables, signal cables, control panels and other electrical parts according to the electrical drawings, ensuring good grounding and stable installation of electrical components.
Instrument configuration:
Install various sensors such as temperature probes, pH electrodes, dissolved oxygen meters, pressure gauges, etc., and calibrate them to normal working conditions.
Control system integration:
Integrate the reactor with its supporting automatic control system (such as PLC or DCS), set and debug various control parameters.
Preliminary startup: Turn on the power, conduct a comprehensive inspection of the control system, confirm that each unit is functioning properly, and execute the preset self-test program.
No load operation: Start the stirring system, temperature control system, ventilation system, etc. of the reactor without biological load, conduct no-load debugging, and test the equipment performance and system stability.
Simulated operation: Use simulated solutions instead of actual biological media for trial operation, test the operation status of the equipment under conditions close to actual operating conditions, and adjust and optimize control strategies.
Introduction of Bioburden: Based on experimental or production plans, introduce microbial or cellular bioburden and gradually adjust it to process conditions suitable for biological growth and metabolism.
Process parameter optimization: Based on the biological reaction process, dynamically adjust parameters such as temperature, pH value, dissolved oxygen, and nutrient supply to achieve ideal product yield and quality.
Safety inspection and verification: Ensure that all safety measures are in place, including over limit alarms and effective emergency stop functions, and conduct verification of CIP (Cleaning in Place) and SIP (Sterilization in Place) systems.
Performance evaluation and acceptance: Test and evaluate various performance indicators of the bioreactor, record debugging results, and conduct formal acceptance after meeting design expectations and user requirements.
Certificate
FAQ
We're professional stainless steel bioreactor manufacturers and suppliers in China, providing customized industry production solutions to nearly 4,500 companies. We warmly welcome you to wholesale bulk stainless steel bioreactor for sale here from our factory. For price consultation, contact us.
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